Every year, on 31 August, communities across more than 40 countries come together to mark International Overdose Awareness Day (IOAD), the world’s largest campaign dedicated to ending overdose.
Led since 2012 by the Penington Institute, a public health non-profit, IOAD began as a single event and has since grown into a global day of action.
Its aims are to amplify the conversation around overdose, share evidence-based prevention strategies, and encourage everyone, individuals, families, professionals and policymakers alike, to play a part in reducing overdose deaths.
This year’s theme, 25 Years On. Still Needed, reflects a sobering truth: despite decades of awareness-raising, overdose continues to affect people from all walks of life. It is also a reminder that overdose is preventable, and that timely support, education, and evidence-based action can save lives.
Here, we look at why IOAD is still so important, how overdose happens, and the role that drug testing can play in supporting prevention.
Why is International Overdose Awareness Day important?
Despite 25 years of IOAD campaigning, overdose remains a significant public health issue in Ireland.
According to figures published by the Health Research Board (HRB) via the National Drug-Related Deaths Index (NDRDI), there were 343 drug poisoning deaths recorded in 2022.
While this marks a decrease on 2021 (343 deaths), the numbers remain a serious concern, with Ireland having previously recorded one of the highest rates of drug-induced deaths in the EU.
Some of the key findings from the 2022 data include:
- Opioids remain the leading cause: opioids, primarily methadone, were involved in 2 in 3 drug poisoning deaths
- A sharp rise in cocaine-related deaths: cocaine was the second most common cause, involved in 1 in 3 drug poisoning deaths. Cocaine poisoning increased by 259% between 2013 and 2022 – the largest increase of any drug group
- Poly-drug use as a major factor: almost 8 in 10 poisonings involved more than one drug, with methadone, diazepam, alprazolam, pregabalin and zopiclone among the most implicated substances alongside cocaine and heroin
- Alcohol as a contributing factor: alcohol was implicated in 1 in 5 drug poisoning deaths, typically alongside other substances
- Who is most affected: the median age of those who died was 45 for men and 46 for women, and almost 1 in 2 people were alone at the time of the poisoning. Of those affected, 2 in 5 had a history of mental health issues, and more than 1 in 10 were experiencing homelessness
Another trend to be aware of is the emergence of nitazenes, a class of potent synthetic opioids, in the Irish drug supply.
According to the European Union Drugs Agency (EUDA), nitazenes caused localised poisoning outbreaks in Ireland in 2023/24, having been mis-sold as heroin and benzodiazepines, resulting in multiple overdoses, and prompting the HSE to issue national health alerts.
This reflects a growing pattern seen elsewhere in Europe and the UK, where unregulated substances are increasingly cut or substituted with more dangerous compounds.
How does an overdose happen?
Understanding how an overdose occurs is an important part of prevention.
An overdose happens when a person has more of a drug, or a combination of drugs, in their body than it can safely process.
Every drug, including illegal, prescribed and over-the-counter drugs, has a threshold beyond which the body struggles to cope, causing vital functions such as breathing and heart rate to become dangerously suppressed or disrupted. This is what makes overdose potentially fatal.
A few important points to understand:
- Overdose isn’t limited to illegal drugs
Medication prescribed by a doctor, such as opioid painkillers or benzodiazepines, can cause an overdose if taken in higher doses than intended or combined with other substances, including alcohol - Mixing substances increases risk
Poly-drug use – taking more than one substance at a time – is involved in most drug-poisoning deaths. Combining depressants such as opioids, benzodiazepines and alcohol is particularly dangerous, as their effects can compound one another - Contamination is a growing concern
The illicit drug market is unregulated, meaning substances are often cut, mixed or substituted without the user’s knowledge – a major contributing factor in the localised drug poisonings and overdoses in Ireland in 2023/24 - Overdose can be fatal or non-fatal
A non-fatal overdose can still cause serious, lasting harm, and often serves as a critical warning sign that support is urgently needed
Learn more: Buyer beware – what are users really getting when they buy drugs on the street?
Overdose prevention: how drug testing can help
Overdose is preventable, and prevention starts with awareness, honest conversations, and access to accurate information.
While no single intervention can eliminate risk entirely, understanding what substances are present in a person’s system can play a valuable role in identifying concerns early and supporting safer outcomes.
At AlphaBiolabs, we have over 20 years’ experience providing drug testing for peace of mind, legal, and official matters.
- At-home drug testing: For those seeking reassurance or clarity about a loved one’s drug use, our peace of mind, at-home drug tests offer a discreet, affordable way to get answers. Our range includes urine, hair and nail drug tests
- Legal drug testing: Our court-approved drug testing services provide reliable, legally admissible evidence for family law professionals, Tusla and the courts: supporting safeguarding decisions and helping to protect children and families in cases where substance misuse is a concern
- Drug testing for private legal & official matters: Our court-approved drug tests are also available for private individuals looking for drug testing for legal or official purposes. Reasons you might need a private legal drug test:
- Contractors or consultants starting work
- Child access or divorce proceedings
- Industrial tribunals
- Other legal issues such as driving offences
- Workplace drug testing: Our workplace drug testing services help employers meet their duty of care, identify potential risks, and maintain safe working environments. This is especially useful in safety-critical industries, where being under the influence of drugs could lead to workplace incidents or accidents, putting other employees at risk
This International Overdose Awareness Day, we’re proud to stand alongside the global community working to raise awareness, reduce stigma and, ultimately, save lives.
To find out more about our drug testing services visit this page, or contact us on 01 402 9466 / info@alphabiolabs.ie. Our expert team can advise on the most suitable drug tests so suit your circumstances.

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